Impact of mirna in atherosclerosis

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August undefined, 2024

Witryna19 sie 2024 · Atherosclerosis remains the leading cause of a broad spectrum of deadliest cardiovascular diseases. MicroRNA‐33 is a new therapeutic target for atherosclerosis due to its diverse functions. However, it remains a great challenge in clinical translation of nucleic acid‐based microRNA‐targeting therapeutics. … WitrynaMoreover, miRNAs are present in peripheral blood with high stability and have the potential to be used as non-invasive biomarkers for the diagnosis of atherosclerosis. However, the circulating miRNA profile may vary according to the involved arterial territory, considering that atherosclerosis expression, including the associated …

A 2 miRNAs-based signature for the diagnosis of atherosclerosis

WitrynaThis review highlights the impact of microRNA-33-mediated regulation in the major cardiometabolic risk factors of atherosclerosis including lipid metabolism (HDL biogenesis and cholesterol homeostasis, fatty acid, phospholipid and triglyceride, bile acids metabolism), inflammatory response, insulin signaling and glucose/energy … WitrynaBACKGROUND: Oxidative stress is a new risk factor for atherosclerosis. Increased oxidative stress in hemodialysis (HD) patients may arise from uremia-associated metabolic/humoral abnormalities and bi darwin realty il

The roles of microRNAs in atherosclerosis - PubMed

Witrynascientific article published on 01 September 2024 Witryna22 lip 2024 · The authors hypothesized that ACP5, as a direct target of lncRNA-H19, causes atherosclerosis by affecting cellular proliferation and apoptosis (Huang et al. 2024). Many studies have reported that lncRNA-H19 functions as a ceRNA to sponge its target miRNAs such as microRNA let-7 (Hsu et al. 2014; Sun et al. 2024b; Cao et al. … Witryna24 cze 2024 · The inhibition of miR-33 using pHLIP-directed macrophage targeting improves atherosclerosis regression by increasing collagen content and decreased … darwin realty elmhurst

Impact of miRNA in Atherosclerosis,Arteriosclerosis, …

Witryna3 sty 2024 · Introduction: Atherosclerosis is a chronic disease characterized by the inflammatory process and lipid depositions. We previously reported that microRNA-216a (miR-216a) can accelerate the progression of atherosclerosis by promoting the polarization of M1 pro-inflammatory phenotype. Ginsenoside Rb2 (Rb2), the major … WitrynaAtherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its onset and progression. Nutrients have been shown to regulate the miR-17/92 cluster, with a role in endothelial function and atherosclerosis. Choline, betaine, and L-carnitine, found in animal foods, are metabolized into trimethylamine (TMA) by the gut … bitch is goneWitryna17 gru 2024 · This study presents novel evidence linking miR-155 biology with the progression and regression of atherosclerosis. Herein, we have shown an inverse … bitch is crazy

"WitrynaAtherosclerosis and lipid biology. Adenylate cyclase type 9 antagonizes cAMP accumulation and regulates endothelial signalling involved in atheroprotection. ... Regulation and impact of cardiac lymphangiogenesis in pressure-overload-induced heart failure. Coraline Heron, Anais Dumesnil, Mahmoud Houssari, ... " - Impact of mirna in atherosclerosis

Impact of mirna in atherosclerosis

Site‐Specific MicroRNA‐33 Antagonism by pH ... - Semantic Scholar

Witryna1 wrz 2014 · Atherosclerosis is a chronic, inflammatory disease of the arterial wall that underlies many of the common causes of cardiovascular morbidity and mortality, including myocardial infarction (MI), and cerebrovascular and peripheral vascular disease. Early pathological descriptions viewed atherosclerosis as an end-stage … WitrynaDownload scientific diagram The screened miR-342-5p facilitated the apoptosis of HUVECs impaired by H2O2. (A) The heat map of top-30 upregulated miRNAs ranked by log2FC value in RNA-sequencing ...

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Witryna13 gru 2024 · Circulating MiRNAs as Potential Clinical Biomarkers for Atherosclerosis and CVD. Extensive research has revealed that miRNAs are extremely stable and … Witryna27 lip 2024 · These findings imply that miR-142-5p may plays a role in the development of atherosclerosis. Next, we tested the effect of miR-142-5p on the 3′-UTR of ABCA1 using luciferase reporter constructs and demonstrated that miR-142-5p dose-dependently reduced mouse and human ABCA1 3′-UTR activities (Figure S11A and …

WitrynaNational Center for Biotechnology Information Witryna19 lut 2016 · The recent emergence of microRNAs (miRNAs) as important regulators of pathophysiological processes, such as cellular adhesion, proliferation, lipid uptake …

WitrynaScience Volunteer Witryna9 maj 2024 · microRNAs (miRNAs) are implicated in the development of a wide range of diseases, including atherosclerosis, obesity, and diabetes (5–8).Among these miRNAs, aberrant let-7 expression is associated with diseases including liver and lung fibrosis and cancer (9,10).In the context of diabetes-associated atherosclerosis (DAA), previous …

Witryna13 kwi 2024 · Liu YL. Effect of microRNA-155 on immune inflammatory response in atherosclerosis [Master]: Tianjin Medical University; 2024. 23. Nazari-Jahantigh M, …

Witryna13 kwi 2024 · Liu YL. Effect of microRNA-155 on immune inflammatory response in atherosclerosis [Master]: Tianjin Medical University; 2024. 23. Nazari-Jahantigh M, Wei Y, Noels H, Akhtar S, Zhou Z, Koenen RR, et al. MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. The Journal of clinical … bitch is crazy songWitryna21 kwi 2024 · MicroRNA dysregulation occurs in many human diseases, including atherosclerosis. Here, we examined the serum expression and clinical significance … bitch islandWitryna11 lut 2024 · Importantly, various miRNAs can regulate the atherosclerosis process, such as miR-21. MiR-21 is the most abundant miRNA in macrophages and can regulate macrophage expression of inflammatory cytokines, such as IL-10 (48–50). Thus, modifying miR-21 in macrophage-derived exosomes has the potential to exert a … bitchis smoke and dropeWitryna18 maj 2024 · To determine the influence of advanced atherosclerosis on the levels of miRNA expression in coronary plaques, we performed initially a miRNA profile using … darwin recliner chairsWitrynaDownload scientific diagram The screened miR-342-5p facilitated the apoptosis of HUVECs impaired by H2O2. (A) The heat map of top-30 upregulated miRNAs ranked … bitch is u blindWitrynaAtherosclerosis is a condition caused by lipid-induced inflammation of the vessel wall orchestrated by a complex interplay of various cell types, such as endothelial cells, smooth muscle cells, and macrophages. ... we outline the effects of miRNA-145, -126, and -155 in atherosclerosis in vivo. Downregulation of miR-145, which controls ... bitch is deadWitryna1 wrz 2024 · Request PDF On Sep 1, 2024, Yao Lu and others published Impact of miRNA in Atherosclerosis Find, read and cite all the research you need on … darwin reforged