Cytoplasmic neat1 suppresses aml

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August undefined, 2024

WebDec 1, 2024 · NEAT1 is a promising biomarker and an ideal therapeutic candidate for immune diseases. • The risk and concern about gene therapy targeting NEAT1 is proposed. (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) has been shown to be involved in the pathogenesis of several diseases. WebAug 1, 2024 · Cytoplasmic NEAT1 Suppresses AML Stem Cell Self-Renewal and Leukemogenesis through Inactivation of Wnt Signaling. 2024, Advanced Science. Increasing Complexity of Molecular Landscapes in Human Hematopoietic Stem and Progenitor Cells during Development and Aging.

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WebNov 17, 2024 · Collectively, the findings show NEAT1_1 is translocated from the nucleus to the cytoplasm and acts as a tumor suppressor in AML. NEAT1 is downregulated in acute … http://www.cloud-clone.com/topic/Recent-advances-in-the-mechanism-of-acute-myeloid-leukemia.html red nativity background

Cytoplasmic NEAT1 Suppresses AML Stem Cell Self‐Renewal and ...

WebJan 26, 2024 · NEAT1 Suppresses AML Stem Cell Self-Renewal and Leukemogenesis through Inactivation of Wnt Signaling As an essential component of paraspeckles, nuclear paraspeckle assembly transcript 1 (NEAT1) localizes in the nucleus, promoting progression of various malignant solid tumors. WebNational Center for Biotechnology Information http://english.ibp.cas.cn/resources_23473/latest_important_articles/index_13.html richard villers cotterets

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WebArticle Title: Cytoplasmic NEAT1 Suppresses AML Stem Cell Self‐Renewal and Leukemogenesis through Inactivation of Wnt Signaling doi: 10.1002/advs.202400914 … WebApr 17, 2024 · Cytoplasmic NEAT1_1 has also been described as a regulator of stem cell self-renewal in acute myeloid leukaemia (AML) [ 48 ]. In contrast to its role in breast cancer, however, NEAT1_1 functions as a tumour suppressor in non-transformed blood cells. richard villerealWebFlow cytometry showed that the upregulation of NEAT1 and SMC1A or repression of miR-23a-3p promoted apoptosis and affected the cell cycle. NEAT1 repressed the expression … richard vimont lexington ky

"WebMar 29, 2024 · NEAT1: A Novel Long Non-coding RNA Involved in Mediating Type 2 Diabetes and its Various Complications. Mechanism of miR-340-5p in laryngeal cancer … " - Cytoplasmic neat1 suppresses aml

Cytoplasmic neat1 suppresses aml

LncRNA NEAT1 regulates HCV-induced Hepatocellular carcinoma …

WebApr 7, 2024 · Background Acute myeloid leukemia (AML) is a heterogeneous hematological disease. Our purpose of the research was to investigate the regulatory influence of long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1)/microRNA-338-3p (miR-338-3p)/CREB3 regulatory factor (CREBRF) in AML progression. Methods The … WebMar 23, 2024 · Cytogenetically normal acute myeloid leukemia (CN-AML) is a heterogeneous disease with different prognoses. Researches on prognostic biomarkers …

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WebOct 13, 2024 · It is demonstrated that NEAT1_1 suppresses leukemogenesis and LSC function but is dispensable for normal hematopoiesis. Mechanistically, NEAT1_1 is … WebApr 17, 2024 · Cytoplasmic NEAT1 Suppresses AML Stem Cell Self-Renewal and Leukemogenesis through Inactivation of Wnt Signaling. Adv Sci (Weinh). …

WebCytoplasmic NEAT1 Suppresses AML Stem Cell Self‐Renewal and Leukemogenesis through Inactivation of Wnt Signaling. Huiwen Yan; Zhi Wang; Yao Sun; Liang-Ding Hu; Pengcheng Bu; Advanced Science. Published on 05 Oct 2024. 0 views XX downloads; XX citations; A Retrospective Observation of Treatment Outcomes Using Decitabine … WebThe aim of this study was to determine the function of the NEAT1/miR-23a-3p/SMC1A axis in cell proliferation and apoptosis in acute myeloid leukemia (AML). Microarray analysis was used to screen differentially expressed lncRNAs/miRNAs/mRNAs in primary AML cells. The expression of nuclear paraspeckle …

WebHerein, an adverse effect of NEAT1 is reported, showing that the short isoform, NEAT1_1 suppresses acute myeloid leukemia (AML) development. NEAT1_1 is downregulated in … WebCytoplasmic NEAT1_1 has also been described as a regulator of stem cell self-renewal in acute myeloid leukaemia (AML) [48]. In contrast to its role in breast cancer, however, …

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WebOct 5, 2024 · Herein, an adverse effect of NEAT1 is reported, showing that the short isoform, NEAT1_1 suppresses acute myeloid leukemia (AML) development. NEAT1_1 … richard visone visone holistic healing centerWebJul 20, 2024 · BackgroundChronic myeloid leukemia (CML) is an acquired hematopoietic stem malignant disease originating from the myeloid system. Long non-coding RNAs (lncRNAs) have been widely explored in cancer tumorigenesis. However, their roles in CML remain largely unclear.MethodsThe peripheral blood mononuclear cells (PBMCs) and … red natura 2000 asturiasWebMar 15, 2024 · The four major types of leukemia are acute myelogenous leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myelogenous leukemia (CML) and chronic lymphocytic leukemia (CLL). The acute form of leukemia usually affects younger individuals and is more severe due to its sudden onset and rapid proliferation. richard vipond public health england